| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5274255 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
A series of novel spiro-isoxazoline/acridinone hybrids has been synthesized regio- and stereoselectively via three-component sequential reactions of 3,4-dihydroacridin-1(2H)-one, aromatic aldehydes and benzohydroximinoyl chlorides in the presence of potassium hydroxide at ambient temperature in good yields. This one pot three-component sequential transformation proceeds via Knoevenagel condensation/1,3-dipole generation/1,3-dipolar cycloaddition sequence.
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