| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5274258 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
A solid-phase methodology to construct aminobenzimidazole tethered sultams and benzothiazepinones from commercial amino acids, amines, carboxylic acids, and sulfonyl chlorides is described. Coupling of Fmoc-Cys(Trt)-OH to resin-bound aminobenzimidazole scaffold provided an essential precursor for the construction of a variety of seven membered benzofused cyclic sulfonamides and thiazepinones via palladium catalyzed Buchwald-Hartwig type intramolecular cyclization.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sureshbabu Dadiboyena, Adel Nefzi,