Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5274311 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
A novel sorbicillinoid named sorbiterrin A (1), possessing an unprecedented skeleton was isolated from a marine sediment derived fungus Penicillium terrestre. The structure including absolute stereochemistries was elucidated by analysis of NMR, MS data and TDDFT CD calculations. Sorbiterrin A showed moderate acetylcholinesterase (AChE) inhibitory effect with IC50 25 μg/mL.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Li Chen, Tianjiao Zhu, Yuanqing Ding, Ikhlas A. Khan, Qianqun Gu, Dehai Li,