Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5274335 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
A three-component coupling of aldehyde, homoallylic alcohol and aryl thiol has been achieved in the presence of trifluoroacetic acid in dichloromethane at room temperature to produce 4-arylthiotetrahydropyrans in good yields with all cis-selectivity. This method is simple, selective and convenient for introducing a thiol group on a tetrahydropyran ring.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
J.S. Yadav, B.V. Subba Reddy, Y. Jayasudhan Reddy, N. Sivasankar Reddy,