Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5274358 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
o-Carboranyl aminoalcohols were synthesized using a standard Mannich reaction, and were tested for their anticancer properties using an in vitro test for CT26 cancer cells. The polar periphery of the aminoalcohols benefited from the high boron uptake in CT26 cancer cells with low toxicity, indicating their potential as BNCT agents.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Chai-Ho Lee, Guo Fan Jin, Jung Gun Joung, Jong-Dae Lee, Hyun Seung Ban, Hiroyuki Nakamura, Jung-Keun Cho, Sang Ook Kang,