| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5274504 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
A multicomponent assembly process (MCAP) was utilized to prepare versatile intermediates that are suitably functionalized for subsequent cyclizations via Ullmann and Heck reactions to efficiently construct substituted 2,6-methanobenzo[b][1,5]oxazocines and 1,6-methanobenzo[c]azocines, respectively. The intramolecular Ullmann cyclization was conducted in tandem with an intermolecular arylation that enabled the rapid syntheses of a number of O-functionalized methanobenzoxazocines.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
James J. Sahn, Stephen F. Martin,