Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5274511 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
A series of 2-(S)-isopropyl-pyrimidinones functionalized at C5 with triazole rings, in which the substituents are found at N-1â² of the triazole ring, were synthesized. Through the azide-acetylene cycloaddition reaction, using CuI as a copper source and ultrasonic waves as an energy source it was possible to obtain products with yields ranging from 79% to 89% within 5Â min or less. A preliminary study to gain further insight into the reaction was performed using in situ ReactIR technology.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hélio A. Stefani, Mônica F.Z.J. Amaral, Flávia Manarin, Rômulo A. Ando, Nathália C.S. Silva, Eusebio Juaristi,