Article ID Journal Published Year Pages File Type
5274532 Tetrahedron Letters 2011 5 Pages PDF
Abstract

We report on the chemoselective coupling between colorless peptide fragments functionalized with a mutually reactive electron-rich Nα-(4-ethynylphenyl)-Nα-(methyl)-glycyl- and an electron-deficient [4-(2,2-dicyanovinyl)]benzoyl moiety. The resulting donor-substituted 1,1-dicyanobuta-1,3-dienes represent a new class of orange-red colored (λmax = 450-500 nm, with molar extinction coefficients (ε) above 5,000 mol−1 dm3 cm−1) peptide-based imaging chromophores.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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