Article ID Journal Published Year Pages File Type
5274572 Tetrahedron Letters 2009 4 Pages PDF
Abstract

The enyne, ubiquitous in natural products, can be a challenge to generate since these moieties require many synthetic transformations to assemble them. We developed a simpler protocol to construct enynes while we found that this oxidative reaction was tolerant in substrate scope. In addition, the utility of this reaction was demonstrated through the attempt in synthesizing antifungal agent Lamisil™.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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