Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5274576 | Tetrahedron Letters | 2009 | 5 Pages |
Abstract
The three-component organocatalysed Mannich type reaction is carried out in a green co-solvent of ethanol and water at room temperature using adenine as catalyst and hydrogen peroxide as additive. The Mannich products are obtained in considerably good diastereoselectivity depending on the effects of substituents on aniline.
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