Article ID Journal Published Year Pages File Type
5274576 Tetrahedron Letters 2009 5 Pages PDF
Abstract

The three-component organocatalysed Mannich type reaction is carried out in a green co-solvent of ethanol and water at room temperature using adenine as catalyst and hydrogen peroxide as additive. The Mannich products are obtained in considerably good diastereoselectivity depending on the effects of substituents on aniline.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry