Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5274623 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
Various novel 3,5a,6,11b-tetrahydro-2H,5H-chromeno[4′,3′:4,5]thiopyrano[2,3-d][1,3]thiazol-2-ones were synthesized in 60–80% yields via domino-Knoevenagel–hetero-Diels–Alder reactions of 4-thioxo-1,3-thiazolidin-2-one with 3,7-dimethyl-6-octenal, 2-allyloxybenzaldehydes and 2-formylphenyl (E)-3-aryl-2-propenoates with base catalysis. The possibility of stereo- and regioselective cycloaddition was investigated.
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