| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5274668 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
Alkylation of γ- and δ-sultams with (iodomethyl)trimethylsilane followed by treatment of the resultant silanes with tetrabutylammonium fluoride gave rise to sulfur-free unsaturated amines. In particular, N-THP substituted sultams were found to be useful substrates for the alkylation event. A corresponding one-pot transformation involving sultam α-alkylation with (iodomethyl)magnesium chloride is also reported.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
