Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5274698 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
The N,Nâ²-disubstituted urea derivatives such as amino acid hydantoins and dihydrouracil derivatives were prepared starting from natural and unnatural amino acid esters using dibutylphosphate (DBP). During the attempted synthesis of N-heterocycles with larger than six-membered rings containing the N,Nâ²-disubstituted urea functionalities, three unexpected products namely squamolone, N-methyl pyrrolidine-2-one, and diketopiperazine were isolated.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sumit K. Agrawal, Manisha Sathe, A.K. Halve, M.P. Kaushik,