Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5274720 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
1-Aryl-3,4-dihydroisoquinolines undergo smooth acetoxylation/alkoxylation in the presence of 5 mol % Pd(OAc)2 and a stoichiometric amount of PhI(OAc)2 by means of C-H activation to produce the corresponding acetoxy- and alkoxy-1-aryl-3,4-dihydroisoquinoline derivatives respectively in good yields with high regioselectivity. It is a first example on oxidative functionalization of arenes tethered to dihydroisoquinoline moiety via the C-H activation.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
B.V. Subba Reddy, N. Umadevi, G. Narasimhulu, J.S. Yadav,