Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5274729 | Tetrahedron Letters | 2012 | 5 Pages |
Abstract
A simple one-pot approach for the synthesis of new pyrazolones containing a phenothiazine unit is reported. Compound 4b was evaluated for its antiproliferative activity on a NCI-60 cancer cell line panel and exhibited selective cytostatic activity toward CCRF-CEM, HL-60(TB), K-562, MOLT-4, and RPMI-8226 leukemia cell lines.
Graphical abstractA simple one-pot approach for the synthesis of new pyrazolones containing a phenothiazine unit is reported.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Lavinia Baciu-Atudosie, Alina Ghinet, Dalila Belei, Philippe Gautret, Benoît Rigo, Elena Bîcu,