| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5274776 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
This paper describes a one-pot procedure for acetamide synthesis directly from amines and pyrimidine ester, without any catalyst or coupling agents. The inexpensive and simple reaction conditions are the most important features of this amidation. This reaction was performed with various amines, showing that long range stabilizing interactions (H-bonding and Ï-stacking) are the driving force for chemoselectivity.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Olivier Rezazgui, Benjamin Boëns, Karine Teste, Julien Vergnaud, Patrick Trouillas, Rachida Zerrouki,