Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5274782 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
Sodium borohydride is used in combination with a heterogeneous palladium catalyst and acetic acid to selectively reduce the carbon-carbon double bonds of various α,β-unsaturated ketones and related compounds. This simple method is most selective when non-polar solvents such as toluene are used. We observed nearly complete conversion and high selectivities using moderate catalyst loadings. The reactions were typically complete in less than 2 h.
Graphical abstractDownload full-size image
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Alyssa T. Russo, Kerstin L. Amezcua, Vincent A. Huynh, Zach M. Rousslang, David B. Cordes,