| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5274901 | Tetrahedron Letters | 2012 | 5 Pages |
Abstract
Propylphosphonic anhydride (T3P®)-DMSO mediated oxidation of alcohols to carbonyl compounds and their subsequent cyclization with aryl/hetero aryl amines and thioglycolic acid to afford 4-thiazolidinones has been reported. Synthesis of 4-thiazolidinones directly from alcohols has been carried out for the first time. Mild reaction conditions, wide functional group tolerance, ease of work-up, and good yields are the noteworthy features of this protocol.
Graphical abstractR1, R2Â =Â H/Alkyl/Aryl/Heteroaryl and R3Â =Â Aryl/Heteroaryl.Download full-size image
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kothanahally S. Sharath Kumar, Toreshettahally R. Swaroop, Kachigere B. Harsha, Kereyagalahally H. Narasimhamurthy, Kanchugarakoppal S. Rangappa,