Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5274920 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
An efficient two-step approach for the synthesis of naphtho[1,2-b]furans and naphtho[2,1-b]furans has been developed. Various functionalized propargyl alcohols were etherified with α- or β-naphthol under Mitsunobu reaction conditions to give naphthyl 2-propynyl ethers, which underwent a facile microwave-assisted Claisen rearrangement and concomitant anionic cyclization to yield naphthofuran derivatives under basic reaction conditions.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
V.S. Prasada Rao Lingam, Dnyaneshwar H. Dahale, Kagga Mukkanti, Balasubramanian Gopalan, Abraham Thomas,