| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5274934 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
Differential reactivity of the amine functionality in a number of common 1,2-diamine starting materials is exploited to undertake an expedient synthesis of unsymmetrical 2,3,6-trisubstituted quinoxaline and unsymmetrical 2,3,7-trisubstituted pyridopyrazine derivatives.
Graphical abstractA set of unsymmetrical and regio-defined quinoxalines and pyridinopyrazines were prepared. Regioselectivity was established by the use of differential reactivity in an aromatic diamine precursor.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Dan Sherman, Joel Kawakami, Hai-Ying He, Farah Dhun, Raphael Rios, Hu Liu, Weitao Pan, Yong-Jiang Xu, Sang-phyo Hong, Melissa Arbour, Marc Labelle, Matthew A.J. Duncton,