Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5274956 | Tetrahedron Letters | 2007 | 5 Pages |
Abstract
Ionic liquid was found to be an excellent medium for asymmetric Diels-Alder reaction catalyzed by chiral bis(oxazoline)-copper complex. The reactivity and selectivity of reactions were highly dependent upon the property of the ionic liquids. Reactions of β-substituted acryloyl dienophiles in [Bmim]SbF6 at ambient temperature provided remarkably enhanced reactivity and stereoselectivity compared to homogeneous reactions in non-ionic liquid solvent at â78 °C. Due to the increased reactivity, the amount of metal catalyst could be reduced down to 0.6 mol % without any significant selectivity compromise. Additionally, recycling of the ligand-metal complex was achieved efficiently up to 18 times.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Chang-Eun Yeom, Hye Won Kim, Yong Je Shin, B. Moon Kim,