| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5274958 | Tetrahedron Letters | 2007 | 4 Pages |
The synthesis of novel N-Boc- and N-Fmoc protected hemithioindigo-based Ï-amino acids is described. An approach to modulate the thermal stability of a hemithioindigo subunit is presented. Placing the amino-group in the stilbene part from the para- to meta-position leads to an increase of the half-life of the thermally labile E-form from 19Â h to 47Â h.
Graphical abstractThe synthesis of novel N-Boc- and N-Fmoc protected hemithioindigo-based Ï-amino acids is described. An approach to modulate the thermal stability of a hemithioindigo subunit is presented. Placing the amino-group in the stilbene part from the para- to meta-position leads to an increase of the half-life of the thermally labile E-form from 19Â h to 47Â h.Download full-size image
