Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5274975 | Tetrahedron Letters | 2011 | 5 Pages |
Abstract
An efficient and original Ugi multicomponent reaction of aminopyridines and aminopyrimidines is reported. Starting from aminotetrazine 6 or 7, an isocyanide and an ortho-carboxybenzaldehyde, tetrazinoimidazoisoquinolinones were isolated, after few minutes of microwave irradiation, in good to excellent yields. The scope of this method was extended by using different isocyanides.
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