| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5274980 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
A series of tetrahydroisoquinolin-pyrrolopyridinones were prepared from an easily accessible aldehyde, a commercially available amine, a readily isolable isonitrile, and maleic anhydride via a triple process: Ugi-3CR-aza Diels-Alder/S-oxidation/Pummerer. The combination of a multicomponent Ugi-type reaction with other post-functionalization processes provides a powerful tool for the preparation of fused polyheterocyclic compounds.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Alejandro Islas-Jácome, Eduardo González-Zamora, RocÃo Gámez-Montaño,