| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275028 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
Two regioselective synthetic routes for 1-N-alkyl-3-aryl-4-[pyrimidin-4-yl]-pyrazoles of generic formula 1 were developed. These highly efficient and scalable routes circumvent the generally observed poor regioselectivity for the pyrazole alkylation.
Graphical abstractTwo regioselective synthetic routes for 1-N-alkyl-3-aryl-4-[pyrimidin-4-yl]-pyrazoles of generic formula 1 were developed. These highly efficient and scalable routes circumvent the generally observed poor regioselectivity for the pyrazole alkylation.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Two convenient regioselective syntheses of 1-N-alkyl-3-aryl-4-[pyrimidin-4-yl]-pyrazoles](/preview/png/5275028.png "First Page Preview: Two convenient regioselective syntheses of 1-N-alkyl-3-aryl-4-[pyrimidin-4-yl]-pyrazoles")
Authors
Jeffrey M. Ralph, Thomas H. Faitg, Domingos J. Silva, Yanhong Feng, Charles W. Blackledge, Jerry L. Adams,