| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275075 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
Enantioenriched tetrasubstituted thiochromanes have been synthesized using a tandem Michael addition-Knoevenagel reaction between 2-mercaptobenzaldehydes and benzylidenemalonates with a 9-epi-aminoquinine thiourea derivative as the catalyst. Steric and electron effects were found to affect profoundly the enantioselectivity and diastereoselectivity of the reaction.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Rajasekhar Dodda, Tanmay Mandal, Cong-Gui Zhao,