| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275077 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
The sequential reaction of 1,2-dihalobenzenes with aryllithiums followed by palladium-catalyzed cross-coupling reactions with Grignard reagents and arylboronic acids is described. This sequential reaction provides a convenient and expeditious access to tri-ortho substituted biaryl derivatives.
Graphical abstractNon-transition metal-catalyzed reactions of 1,2-dihalobenzene with aryllithiums followed by palladium-catalyzed cross-coupling reactions of Grignard reagents and arylboronic acids to form tri-ortho substituted biphenyls are described.Download full-size image
Related Topics
Physical Sciences and Engineering
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Authors
Ping He, Cheng-Guo Dong, Qiao-Sheng Hu,