Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5275138 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
A three-component coupling of aldehydes, homoallylic alcohols and ammonium thiocyanate is achieved in the presence of 10 mol % of In(OTf)3 in refluxing dichloromethane to produce 4-thiocyanotetrahydropyrans in excellent yields with all cis-selectivity. This method is simple, selective and convenient for introducing an SCN group onto a tetrahydropyran ring.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
J.S. Yadav, B.V. Subba Reddy, Tapas Maity, G.G.K.S. Narayana Kumar,