| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275147 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
A library of new chiral iminoalkyl imidazolium salts has been synthesised from amino acids using a modular design approach. Deprotonation with silver oxide yields silver carbene transfer reagents, which can be used as ligand sources in asymmetric catalysis. Preliminary testing has shown that the ligands induce enantioselectivity in the palladium-catalysed allylic alkylation of 1,3-diphenylprop-3-enyl acetate with dimethyl malonate.
Graphical abstractChiral iminoalkyl N-heterocyclic carbenes were generated from imidazolium salts, which were prepared from chiral amino alcohols and substituted imidazoles.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mahboub Merzouk, Theo Moore, Neil A. Williams,