| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275180 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
N-Acylhomoserine lactones (AHLs) are the conserved quorum-sensing signal molecules in Gram-negative bacteria. (Z)-N-(4-Decenoyl)homoserine lactone (1), a new AHL, was isolated from the culture broth of the fungus Mortierella alpina A-178 harboring bacterial endosymbionts, called endobacteria. The structure and absolute configuration of 1 were elucidated by EI-MS, chemical synthesis, and chiral GC analysis. The compound induced the expression of a QS-regulated reporter gene in Agrobacterium tumefaciens NTL4, although its activity was lower than that of N-decanoylhomoserine lactone (6).
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kenji Kai, Koji Kasamatsu, Hideo Hayashi,