Article ID Journal Published Year Pages File Type
5275245 Tetrahedron Letters 2011 4 Pages PDF
Abstract

The effects of trace amounts of water on thiocarbamate- and thiourea-catalyzed bromolactonization reactions are studied. It was found that the thiourea- and the N-Me thiocarbamate-catalyzed bromolactonization reactions were sensitive to trace amounts of moisture. In contrast, the N-H thiocarbamate-catalyzed bromolactonization proceeded equally smoothly in both anhydrous and non-anhydrous solvents.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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