Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5275252 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
Stabilized 2-amino-1,3-dienes can participate in intramolecular Diels–Alder (IMDA) reactions with pendant dienophiles. We found that these dienes can be readily prepared via standard palladium-mediated coupling reactions and have comparable reactivity to 2-oxodienes. Application of these substrates to the synthesis of tetracyclic model systems representing the ABCE motif of the zoanthamines is presented.
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