| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275281 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
A new synthetic pathway has been developed for the preparation of imine-containing pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) and their dimers. Selective reduction of aromatic azides as well as aliphatic amides in a single step leading to an intramolecular reductive cyclization process by employing LiAlH4 or LiBH4 provides the cyclized imines.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ahmed Kamal, N. Shankaraiah, N. Markandeya, K. Laxma Reddy, Ch. Sanjeeva Reddy,