Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5275284 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
Enantioselective Friedel-Crafts alkylation of simple phenols (4a-j) with 3,3,3-trifluoropyruvate (3) was accomplished by using chiral cinchona alkaloid catalyst 2h (10 mol %). High yields and enantioselectivities (71-94% ee) of the Friedel-Crafts alkylation products were obtained.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jun-Ling Zhao, Li Liu, Chun-Ling Gu, Dong Wang, Yong-Jun Chen,