Article ID Journal Published Year Pages File Type
5275284 Tetrahedron Letters 2008 4 Pages PDF
Abstract
Enantioselective Friedel-Crafts alkylation of simple phenols (4a-j) with 3,3,3-trifluoropyruvate (3) was accomplished by using chiral cinchona alkaloid catalyst 2h (10 mol %). High yields and enantioselectivities (71-94% ee) of the Friedel-Crafts alkylation products were obtained.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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