Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5275293 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
A highly efficient total synthesis of (R)-(+)-muscopyridine 1 has been accomplished in 12 steps with 40% overall yield. A highlight of the synthesis is the intramolecular [4+2] cycloaddition of bisketene to afford a bridged pyrone and ring transformation of the pyrone to afford pyridine derivatives.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kie Suwa, Yasuko Morie, Yumiko Suzuki, Kiyoshi Ikeda, Masayuki Sato,