Metal-free Brønsted acids catalyzed synthesis of functional 1,4-dihydropyridines

Brønsted acids catalyze the addition of β-enaminoacrylates to α,β-unsaturated aldehydes leading to substituted dihydropyridines in moderate to good yields under mild conditions. The first example of an enantioselective synthesis of a dihydropyridine is also reported.

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