Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5275335 | Tetrahedron Letters | 2007 | 5 Pages |
Abstract
Six tail-to-tail amine-linked neodisaccharides were synthesised as potential glycomimetics. Primary-primary linked compounds were synthesised using Mitsunobu chemistry with glucose-6-sulfonamides as nucleophiles and primary carbohydrate alcohols as electrophiles. Primary-secondary linked compounds were synthesised by epoxide ring opening with carbohydrate 6-amines. Deprotection of all neodisaccharides was carried out using dissolving metal reduction.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Tashfeen Akhtar, Ian Cumpstey,