| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275358 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
2-Azidoalcohols derived in situ from epoxides and sodium azide undergo smooth coupling with alkynes under neutral conditions by means of 'click reactions' to furnish β-hydroxytriazoles in excellent yields and with high regioselectivity. This reaction proceeds smoothly in water at room temperature without the need for acid catalysis.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
J.S. Yadav, B.V. Subba Reddy, G. Madhusudhan Reddy, D. Narasimha Chary,