| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275368 | Tetrahedron Letters | 2012 | 5 Pages |
Abstract
The first copper-catalyzed direct three-component coupling reaction of aldehydes, alkynes, and hydroxylamines for the synthesis of propargylamines has been developed under mild conditions, which has the advantages of ready availability of catalyst as well as operation simplicity. The present protocol provides an appealing alternative for the construction of propargylamines in a simple and one-pot procedure.
Graphical abstractThe first copper-catalyzed direct three-component coupling reaction of aldehydes, alkynes, and hydroxylamines for the synthesis of propargylamines has been developed in a simple and one-pot procedure.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Na Guo, Jian-Xin Ji,