Article ID Journal Published Year Pages File Type
5275428 Tetrahedron Letters 2011 4 Pages PDF
Abstract

Basic alumina supported, solvent-free synthesis of novel oxazocines, medium size heterocycles, has been achieved in excellent yields by tandem C-alkylation followed by intramolecular O-alkylation of hydroxyquinoline/isoquinoline(s) with quinolinium salts under microwave irradiation. The method provides a facile and efficient route for the construction of polynuclear bridge-head oxazocines.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry