| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275443 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
A rationally designed 4-phenoxy substituted prolinamide phenols as an efficient hydrophobic organocatalyst for direct asymmetric aldol reaction in water has been developed. High yield (up to 99%), diastereoselectivity (up to 99:1), and enantioselectivity (up to 97%) were obtained under optimal condition. The influence of substituent groups on the reactivity of catalysts was studied in detail.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shu-peng Zhang, Xiang-kai Fu, Shao-dong Fu,