| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275452 | Tetrahedron Letters | 2009 | 6 Pages |
Abstract
An efficient and novel one-pot synthesis of 3,4,5-trisubstituted-3,6-dihydro-2H-1,3-oxazine from alkynoates, anilines, and formaldehyde is described. The six-membered N,O-heterocyclic skeleton was constructed via Brønsted acid-promoted domino hydroamination/Prins reaction/cyclization/dehydration reactions.
Graphical abstractAn efficient and novel one-pot synthesis of 3,4,5-trisubstituted-3,6-dihydro-2H-1,3-oxazine from alkynoates, anilines, and formaldehyde is described. The six-membered N,O-heterocyclic skeleton was constructed via Brønsted acid-promoted domino hydroamination/Prins reaction/cyclization/dehydration reactions.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hua Cao, Huan-Feng Jiang, Chao-Rong Qi, Wen-Juan Yao, Huo-Ji Chen,