Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5275480 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
An efficient acid-catalyzed protection of alcohols as trityl ethers is described using triphenylmethanol in the presence of tris(pentafluorophenyl)borane (3 mol %) in dichloromethane at room temperature. The chemoselectivity of this protocol is demonstrated by studying the tritylation of a primary alcohol in the presence of a secondary alcohol and also the mildness of this catalyst was studied with substrates containing acid labile protecting groups.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ch. Raji Reddy, G. Rajesh, S.V. Balaji, N. Chethan,