Article ID Journal Published Year Pages File Type
5275480 Tetrahedron Letters 2008 4 Pages PDF
Abstract

An efficient acid-catalyzed protection of alcohols as trityl ethers is described using triphenylmethanol in the presence of tris(pentafluorophenyl)borane (3 mol %) in dichloromethane at room temperature. The chemoselectivity of this protocol is demonstrated by studying the tritylation of a primary alcohol in the presence of a secondary alcohol and also the mildness of this catalyst was studied with substrates containing acid labile protecting groups.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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