| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275483 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
A short total synthesis of the cytotoxic natural product pachastrissamine is described. The synthesis includes eight steps starting from Garner's aldehyde and proceeds in 20% overall yield. Pd(0)-mediated intramolecular cyclisation and Ru-mediated cross-metathesis are the key reactions in this sequence.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mikko Passiniemi, Ari M.P. Koskinen,