| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275498 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
Borane-dimethoxyethane generated from sodium borohydride-bromine mixtures efficiently reduces a wide range of malonate derivatives to the corresponding 1,3-diols. This new reagent system represents a milder alternative to current methods available, providing the requisite 1,3-diols in higher yields over shorter reaction times.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Matthew Tudge, Hiroko Mashima, Cecile Savarin, Guy Humphrey, Ian Davies,