Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5275593 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
The first total synthesis of (+)-pentandranoic acid A (1) was accomplished in 14 steps, starting from alcohol 3. Our synthesis features several key transformations, such as an ozonolysis-aldol cyclization-dehydration ring contraction sequence and a selective 1,4-diol oxidation, and provides an efficient synthetic route to this rare clerodane diterpenoid.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Li Ren, Edward Piers,