Article ID Journal Published Year Pages File Type
5275593 Tetrahedron Letters 2012 4 Pages PDF
Abstract

The first total synthesis of (+)-pentandranoic acid A (1) was accomplished in 14 steps, starting from alcohol 3. Our synthesis features several key transformations, such as an ozonolysis-aldol cyclization-dehydration ring contraction sequence and a selective 1,4-diol oxidation, and provides an efficient synthetic route to this rare clerodane diterpenoid.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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