Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5275640 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
A new cembradiene diterpenoid 1, together with the known antiplasmodial cembradiene 2, was isolated from the sea whip Eunicea sp. collected from Santa Marta Bay on the Colombian Caribbean sea. The structures and absolute stereochemistry of 1-2 were determined by extensive spectroscopic analysis, chemical transformation of 2 to the new diterpenoid 3, and by using modified Mosher's method. This is the first known report regarding the determination of the absolute configuration of 2.
Graphical abstractDownload full-size image
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Humberto Mayorga, Norman F. Urrego, Leonardo Castellanos, Carmenza Duque,