| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275657 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
The novel dimethoxyl(aminoalkoxy)borate 1 was isolated as a white crystalline dimer joined by H-bonding as evidenced by X-ray analysis, and demonstrated to be a highly effective catalyst for the asymmetric reduction of representative prochiral ketones with borane–DMS. Optically pure alcohols were obtained using only 1 mol % of catalyst 1 in up to 99% ee.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
