| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275677 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
A Tröger's base derivative (5,12-dimethyl-3,10-diphenyl-1,3,4,8,10,11-hexaazatetracyclo [6.6.1.02,6.09,13]pentadeca-2(6),4,9(13),11-tetraenes) was used as an efficient catalyst for the three-component Mannich reactions of aromatic aldehydes and aromatic amines with ketones in water at room temperature. This rapid reaction afforded the corresponding β-amino ketones in good yields with excellent stereoselectivity.
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Authors
Hui Wu, Xiu-mei Chen, Yu Wan, Ling Ye, Hai-qiang Xin, Hua-hong Xu, Cai-hui Yue, Li-ling Pang, Rui Ma, Da-qing Shi,