| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5275741 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
(Diacetoxyiodo)benzene (PhI(OAc)2) was found to be a powerful reagent to induce the intramolecular oxidative bromocyclization of homoallylic sulfonamides utilizing KBr as the bromine source. The reaction affords 2-substituted-4-bromo-pyrrolidines in moderate to excellent yields under a mild metal-free condition, and offers good manipulability by avoiding the use of highly toxic and caustic bromine (Br2).
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Renhua Fan, Fengqi Wen, Luoheng Qin, Dongming Pu, Bing Wang,